D-ribose is a sugar particle which is essential for your body to produce adenosine triphosphate or ATP. ATP is a basic kind of energy and a type of fuel consumed by the cellular mitochondria.
Naturally, the body cells generate D-ribose, but every organ produces a different amount of D-ribose which is a slow process.
The adrenal glands, the liver and fat tissues are more responsible for producing a high amount of D-ribose.
On the other hand, other body parts such as nerve tissues, the brain, the heart, and muscles produce some amount of D-ribose which meet their everyday requirement.
Difference between ribose and D-ribose?
Table of Contents
Generally, both are same. The term D-ribose refers to Deoxyribose available in DNA which is a natural form of sugar. There L-ribose available, but its synthetic not available in nature. Therefore, when people say ribose, that means D-ribose.
What is the use of ribose?
Many people D-ribose for different reasons such as sports performance, exercise. It is a great energy booster. Primarily its recommended for athletes.
Manufacturers of D-ribose claim that it helps in the following purposes.
- Decrease muscle fatigue
- Speedup recovery after a workout
However, some of the present studies show that ribose doesn’t help sports performance.
The manufacturers of D-ribose advise taking doses of 1 to 10 grams every day.
Ribose is more helpful for individuals with coronary artery ailment. These patients have a problem with blood supply and oxygen while exercise which causes angina or chest pains.
According to some research, the ribose supplement helps to promote the amount of workout for heart patients in a comfortable way. This supplement helps to regulate the heart’s ATP (antitachycardia pacing) levels after angina episode or heart attack.
Some research discovered that ribose helps to boost heart function and life quality in people with congestive heart failure and coronary artery disease.
But these researches are small to consider the conclusion because of not having a comparison or randomized to placebo. Therefore, there is a requirement for more research.
Ribose also useful supplement for preventing cramps, stiffness, and pain after a workout in people with uncommon disease AMPD deficiency.
Benefits of D-Ribose
Adding D-Ribose in your fitness helps to improve overall health and provide working capacity for 24 hours. It helps to generate ATP and boost quick energy which will make you stay active for a long time.
The group of people who have congestive heart failure gets the most benefits of D-Ribose.
During follow up testing discovered that patients improved diastolic function while taking D-ribose that mean their hearts were relaxed in a better way and filled with blood.
According to the report of volunteers, there was an improvement in physical activity and life quality.
Helps in Cardiac Rejuvenation
D-ribose helps to rejuvenating cardiac with its vital nutrients and treat heart disease specifically ischemic heart disease which occurs by coronary artery blockage and results in heart attacks. The restricted blood flow cause to injure heart muscle and become soft which leads to restricting the blood pumping.
The acute drop in adenosine triphosphate (ATP) levels in the heart muscles cells during restricted blood flow and the continued delay in regulating to normal even after proper blood flow causes a heart attack. It is described as an ischemia-reperfusion injury which is a major cause for generating long-term heart damage in heart attack survivors. D-ribose helps to render the tissues exposed to harmful free radicals happen through oxygen-rich re-blood flow in the damaged area.
D-ribose is an important element for building new ATP. According to animal studies, the raised ATP level in severe reperfusion time after heart attack – the time when blood flow is returned, and cells use energy at notably high levels to restore the damage. This produce required energy levels to stop the future injury and begin to heal the damaged tissue.
According to an interventional study confirmed that the effect changes dramatically. The cardiac arrest triggered while certain types of heart surgery like bypass surgery cause a quick decline in heart muscle function even in almost all areas and these effects linked with reducing ATP levels which can cause to delay the surgery recovery. Then the scientist gave D-ribose to the heart while surgery by thinking that it could fuel the heart muscles in advance with an essential element for regulating ATP levels. Finally, scientist discovered the functions improvement in the heart muscles.
Therefore, D-ribose is an important component for ATP under extreme stressful heart problem.
Benefit for chronic fatigue syndrome and fibromyalgia
The muscles stiffness and pain reduce the quality of life. Yet general medicine unable to treat these conditions effectively.
Particularly Fibromyalgia is disease causes muscle symptoms which occur by the insufficient ATP production. This makes sense if your heart is highly responsive to failure while ribose production gets slows, then the muscles also function slow.
A study of 41 individuals with fibromyalgia and chronic fatigue syndrome discovered that D-ribose supplement treats these conditions effectively. During the trial, patients got 5 grams of D-ribose three-time every day for two to three days a week. As a result, in the end, patients reported an improvement in the sleep, energy, pain intensity, mental flexibility, and entire well-being.
D-ribose prevent aging effects
As you begin to age, your collagen levels get affected. Collagen is an important protein in the body which available in connective tissues such as bone, skin, muscle, and joints. While you are unable to make enough collagen, taking ribose supplement helps to reduce muscles pain and joint stiffness. Therefore, taking D-ribose can help to prevent adrenal fatigue and reduce the effect of aging.
Additionally, ribose helps to build ATP block, and collagen build many other proteins blocks in the body. Collagen has different amino acids which human body cannot produce on its own. The amino acid needed to consume by protein food such as meat and supplement to get enough protein for making collagen.
D-ribose is widely promoted as a natural supplement for the enhancement of exercise endurance.
During extended level of high-intensity workout, the skeletal muscle of ATP (adenosine triphosphate) gets exhausted. Due to low levels of ATP, the muscles recovery takes several days which causes to effect on the performance of everyday workout plan.
In some cases, untrained people suffer from the acute stress and consequence due to the feeling of repeated tiredness and the reduced ability to perform.
Whereas trained individuals recover fast because they have enhanced immunity and metabolism. Therefore, a weak individual who is undertaking athlete activities can have R-ribose to get it to benefit for ATP.
D-ribose prevent heart disease
According to studies D-ribose also helpful to prevent heart disease in people with congestive heart failure. These people have reduced the ability to pump the blood vigorously from heart to entire body. It happens due to poor exercise tolerance and lack of energy. In more severe cases complication of lungs and the liver is the cause.
D-ribose for people with congestive heart problem helps to prevent fluid build-up in the entire body and promote energy levels. It helps tissues to get the need nutrients and oxygen from restored blood flow. During the study, the patient reported abundant improvement in their quality of life while taking a supplement. Even, they got motivated to have a good and healthy lifestyle with everyday exercise which essential for managing cardiovascular health.
D-ribose helps restless-legs-syndrome
Restless-legs-syndrome is a type of neurological problem accompanied by pain, annoying sensation and decreased extremities during rest.
The person with restless legs symptoms has an uncontrollable feeling to move for relief.
An experiment went on two affected males – a father age with 71 and son age with 47. They belong to a family with three generations with the diagnosis.
To know the benefit of D-ribose, both the individuals consumed 5-gram doses for each one every day at different trial stages. Every stage continues for 3 weeks and another for 2 weeks.
During the initial stage, D-ribose gave in only breakfast.
In the second stage, D-ribose gave in breakfast and lunch.
In the final stage, D-ribose gave in all meal.
During the initial stage, both father and son felt less fatigue and more energy. They noticed changes in their symptoms after exercise.
In the second stage, they felt twitching and unpleasant sensation at night in the legs.
In the final stage, after taking D-Ribose in all meal reduced their symptoms.
However, both men reported that D-ribose consumption did not completely removed the discomfort but reduced the irritating symptoms without any reactions.
D-ribose helps to Energize Skeletal Muscle
Skeletal muscle is one of three large muscles in the body. It is a kind of striated muscle tissue which works voluntarily to regulate the somatic nervous system. Most of the skeletal muscles are connected to bones with bunches of collagen fiber called as tendons.
Skeletal muscles are important to supply the energy to raise the blood flow and boost the well-being sense.
Keeping a habit of regular exercise is helpful prevention for cardiovascular disease, stroke, and heart attack. Although, only 50% of people have a healthy lifestyle to improve cardiovascular health.
Many people find difficulty in gathering energy even after participating in a moderate physical activity program.
A study discovered that many people stop physical exercise after getting physical fatigue due to exercise. It can be understood that heavy workout cause to drop the muscle ATP level by 20% and require 72 hours to recover back muscles original ability.
According to science, D-ribose works well for energizing muscles. Workout physiologists discover that consuming D-ribose supplement for skeletal muscle increase the complete ATP up to four-fold.
D-ribose benefits seizures
A seizure is an uncontrolled, unexpected electrical disruption in the brain. This sudden change causes variation in feelings, behavior, movements and consciousness levels. If you get multiple seizures or recurrent seizures, then you will have seizures disease.
There are several kinds of seizures which have a different range in severity. The seizure types occur differently depending on the cause and its area in the brain. Most of the seizures occurrence remain from 30 seconds – two minutes. If your seizure condition lasts for more than five minutes, then it requires a medical emergency.
Seizures are a common condition which can occur after an infection in the brain, stroke, or a head injury. There is a possibility that some you may not know the cause of the seizure.
D-ribose can be beneficial for seizures. Comparatively, it can be a cheap therapy for the improving behavior change and reducing seizure frequency.
D-Ribose benefits Adenylosuccinase Deficiency
Adenylosuccinase deficiency is uncommon metabolic condition passes from genes. This condition’s symptoms greatly vary from person to person.
Generally, the affected person will have multiple neurological symptoms including movement and cognitive abnormalities, feeding problem.
However, abnormal physical characteristics such as a small head, abnormal head shape, upturned nostrils low set of ears and thin upper lip.
However, D-Ribose consumption has shown improvement in behavior and seizure frequency.
D-Ribose benefits Kidneys
D-Ribose consumption helps to protect kidney dysfunction and decrease the tissue damage by chemotherapy. It helps to prevent kidney damage happen due to an insufficient blood supply.
D-Ribose benefit your brain
Ribose helps to prevent pro-apoptotic genes activation which is programmed cell death in demonstrating and hippocampus – a neuroprotective impact occurs by abnormal heartbeat.
D-Ribose help weight loss
D-ribose helps to improve your gut motility in mice experiment. It also raises energy which helps in weight loss. D-ribose supplement consumption helps to boost your metabolism while workout but you should not depend only on ribose. You should have a healthy carb, and plenty of fiber meal to lose weight.
How to Use D-Ribose
D-Ribose available in the form of powder. The easiest way to take D-ribose is to mix it with any beverage. As it tastes like sweetener, it will be perfect to add in tea or coffee. You can also add it in yogurt or smoothie.
- The general recommended dosage is 5 grams, two to three times per day.
- Individual performing intense activity can take 5 grams before exercise daily.
- Individuals with muscle cramps can take 5 grams D-ribose after a workout which can ease the cramps.
Regarding the side effects, D-Ribose can cause a digestive problem in some people, but that can be manageable.
If you get the problem, then you can reduce the dosage to resolve the problem.
Some people worry about D-ribose(sweetener) that can cause to increase blood glucose levels. But, no worries, D-ribose will not affect blood sugar levels. In fact, according to evidence, D-ribose manages glucose levels.
If you are a diabetic patient and taking insulin or blood sugar reducing medicine than check with your doctor to prevent hypoglycemia because of D-ribose.
Who should avoid D-ribose?
Usually, D-ribose is reliable for many people when used orally for short time or according to the health care professional. As every person’s health differs from one another, it may induce some side effects such as stomach discomfort, diarrhea, headache, nausea, and low blood sugar.
There is no sufficient information about the safety of long-time usage of D-ribose. If you find d-ribose helpful for your health condition, then make sure to consult your doctor for long-term use.
D-ribose gives the working capacity for 24 hours by decreasing extreme pain and improve the quality of life. Therefore, if you are a healthy person and deprivation of nutrition causing you tired, then you can take D-ribose and enjoy the energetic life.
You may like to know the possible side effects.
Every medicine or supplement works differently for different people. Therefore, you need to watch the following symptoms to know if you are getting any side effects.
- For some people, D-ribose can cause nausea, diarrhea, stomach discomfort and headache.
- People with diabetes may get a drop-in blood sugar level.
- If you are undergoing any surgery than stop D-ribose before two weeks because it may interfere in blood sugar control.
- Taking a large quantity of D-ribose can upset your digestive system.
- Long term consumption of D-ribose may cause memory loss and anxiety.
- D-ribose may affect the people with high blood pressure because your heart requires more energy to pump the blood.
- Women during pregnancy and breastfeeding should avoid D-Ribose.